Val Wood

But this is the case for every siRNA pathway This is PTGS: If you make this split, you are breaking down a 'linear pathway" which includes amplification , for which...

I don't know about miRNAs, but all the pathways which use siRNA have an amplification step. We have never included this in a term before. I think it is a...

Right, there is not always an amplification step, but the ampification when it occurs is performed by RNA dependent RNA polymerase, and so it is a single-step (MF)? Is that...

This split NTR primary piRNA processing NTR secondary piRNA processing sort of works, except that the RNA-dependent RNA polymerase amplification MF isn't processing (processing is specifically producing a mature RNA...

The paper I am reading right now calls this process "production" not processing PMID:15615848 Title | RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly...

Be aware that priRNA 3'-end processing (GO:1990431) already exists, which overlaps somewhat with NTR primary piRNA processing ( it is proably equivalent? ) The process of forming the mature 3'...

woah that is cnfusing. I was confusing pri and pi, but I think they are the same thing. "We have previously identified priRNAs, a class of Dicer-independent small RNAs in...

@mah11 may know.....

The terms might mean the same but in fission yeast we never use apical/basal because uni-cellular organismal cells don't have a 'base'

GO:0061246 seems to have disappeared without notice? At least, I get a message "Session can't be approved as a term ID is not in the database: GO:0061246 " in a...