Val Wood

Hi @kaxelsen any feedback on this?

Any reason why these couldn't be. merged?

If this is obsoleted we need to implement on of the other solutions in the linked ticket first. We can look at this again when we finalize the "ageing" review

7, 4 UniProt @Antonialock 1 complex portal 2 SGD @suzialeksander consider MF [GO:0061860]( DNA clamp unloader activity

Isn't the mRNA cleavage a step in the PTGS pathway? https://pubmed.ncbi.nlm.nih.gov/33184244/ Post-transcriptional gene silencing (PTGS)-mediated gene silencing exploits the cellular mechanism wherein transcripts having sequence similarity to the double-stranded RNA...

OK I see there is a term specifically for PTGS https://www.ebi.ac.uk/QuickGO/term/GO:0035194 and this has the parent gene silencing by RNA. Should the general term be a bit more explicit about...

Actually, I am still confused. The term GO:0098795 global gene silencing by mRNA cleavage has 20 annotations, and they are mainly FlyBase (for dicer, so this is clearly the RNA-dependent...

Can we discuss based on comment? I think the "GO:0098795 global gene silencing by mRNA cleavage" is being used for annotation of genes that should be annotated to the RNAi...

OK, don't worry. Its a bit odd because it is really a "network" and consists of components of the outer and inner kinetochore: Some members are not Ndc80 or MIND...

Here is another schematic https://www.nature.com/scitable/content/the-centromere-kinetochore-region-43815/ Although Ndc and MIND do interact physically and genetically, the complex grouping is a bit odd. I think on balance we don't need NMS, and...