Val Wood

A different opinion: Mis12 is generally considered part of the outer kinetochore. eg see this budding yeast diagram from Sue Biggins and this in fission yeast (Diagrams below) In mammalian...

The papers Alison refers to budding yeast https://elifesciences.org/articles/37819 fission yeast https://cshperspectives.cshlp.org/content/7/7/a018770 ~but look at the fission yeast subunits of Mis12 complex, they are split between inner and outer ?~

so they are

KMN/NMS nomenclature has been around for a long time. The network originally referred to a genetic network the organization was fully known. That's why we obsoleted NMS complex, it was...

So far: - [ ] It makes sense the Mis12 complex moves to outer kinetochore. - [x] I don't think we need a specific NMS term (it would be an...

I think it is good to add based on feedback received. Some people use KLM/CCAN in preference to inner/outer, but we need to be aware that the "constitutive" part can...

hmm, that makes me think that [git7](https://www.pombase.org/gene/SPBC36.12c), [hsp90](https://www.pombase.org/gene/SPAC926.04c) are unlikely to be directly involved in [adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway](https://www.pombase.org/term/GO:0010619) ;) causally upstream?

Takashi wisdom: One review paper (attached) said this complex locates between inner (CCAN) and outer kinetochores (Knl1 and Noc80C) and is assigned as central. As Mis12C is part of KNM...

I think this one can close as out of date. Action is not clear , or is duplicate din other tickets (except GO:0061992 ATP-dependent chaperone mediated protein folding GO:1990507 ATP-independent...

Thanks, we will update the GO definition of Glycoside to match this one. Just to confirm, doe s this mean that **some** disaccharides are glycoside, but **not all** disaccharides are...