Val Wood

~Most of this ticket is wrong. I will update at some point~ In the meantime I wanted to flag this new review on nuclear protein quality control https://pubmed.ncbi.nlm.nih.gov/35760103/l actually thee...

If this is the same mechanism as pombe the unproductive ncRNA transcript is the regulation. it works like this: https://www.pombase.org/reference/PMID:34389684 (click on the summary image to make it bigger) The...

Will need this to replace annotation in the protein modification branch

I will also use for PMID:34389684 (I sill need https://github.com/geneontology/go-ontology/issues/22717 for this paper) and a nice review that would make an additional ref for this term. Long RNA-Mediated Chromatin Regulation...

Actually the parentage needs revising. The lncRNA-mediated gene silencing in PMID:34389684 is transcriptional, not post-transcriptional. Or you need to change the this term to "post-transcriptional lncRNA-mediated gene silencing" (most lncRNA-mediated...

The ones I have are 'transcriptional' but not co -transcriptional. I belive co-transcription occurs during transcription and processing? This is a bit different. The ncRNA prevents transcription (it is itself...

This seems to be g, lncRNAs interfere with Pol II transcription machineries both at the initiation (left) and elongation (right) stages. in https://github.com/geneontology/go-ontology/issues/23028 (specifically left, iniitiation)

Right so there will be no terms for ncRNA-mediated gene silencing (presumably because the entity is a lncRNA so it unnecessary to capture this in a term? is that correct?

>First of all I dont think 'actin filament' should contain 'associated proteins' (current def= "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins....

I think that is a good plan....