MuSiC
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Multi-subject Single Cell Deconvolution
Hi, here. We used the ExpressionSet function to build the input datasets and run the MuSiC. However, there were something wrong. The single-cell datasets and bulk datasets were as follows....
Hello, sadly loading the Rdata file does result in two character-lists and not one RObject. Best
Dear sir, I used 'music_prop()' function to get the estimated proportion of diffenrent cell types. But i also want to get a expression martix of one cell types. So how...
Hi Xuran, We want to apply the MuSiC algorithm to snRNA-seq and bulk RNA-seq data. If we look at RPKMs from the top40 marker genes from our snRNA-seq data, we...
@xuranw Hi Xuran, Really appreciate you developed this awesome R package. I have a question regarding R-squared. Could you please briefly describe how r-squared is calculated? Why R-squared is negative...
Hi Xuran, In the tutorial section "Estimation of cell type proportions with pre-grouping of cell types", I wonder how you selected genes for group.marker. It did mention 'intra-cluster differentially expressed...
Thank you for this package. I recently received this error stop("Not enough valid cell type!") I was wondering if this was because there is a minimum number of single cell...
Thank you for writing this great package. One small issue: I tried running the example in the tutorial, but with `ct.cov = TRUE`. I get the error `object 'i' not...
Hi. I have encountered this problem in my code. what is going on? ``` tmp
Hi Xu Ran Many thanks for developing MuSiC! I really like the idea of giving each gene a weight instead of establishing an overall cutoff w signature matrix. I am...