Multi-subject Single Cell deconvolution (MuSiC)

MuSiC is a deconvolution method that utilizes cross-subject scRNA-seq to estimate cell type proportions in bulk RNA-seq data.

How to cite MuSiC

Please cite the following publication:

Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
X. Wang, J. Park, K. Susztak, N.R. Zhang, M. Li
Nature Communications. 2019 Jan 22 https://doi.org/10.1038/s41467-018-08023-x

Installation

# install devtools if necessary
install.packages('devtools')

# install the MuSiC package
devtools::install_github('xuranw/MuSiC')

# load
library(MuSiC)

More Information

Please see Tutorial.