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A cool place to store your Hi-C

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Hi! I ran cooler balance with my cool file and it ran okay until it reached an error Output exceeds the size limit. Open the full output data in a...

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Workaround TypeError exception raised by `cooler.annotate()` when bin ids in `/pixels` table are stored as unsigned integers. The exception is due to the implicit conversion to `float` performed by numpy...

Hi, I am quite new with the cool format and I am not able to understand how to do this. I have a genome-wide .cool matrix and to perform some...

Hi author: When i run cooltools to identify the A/B compartment, I get an error message that 'Unable to open object (component not found)'. I guess this is input file...

Hi Nezar, I have created a cool matrix based on a restriction cut site resolution. If I try to load data via ``` cool_obj.matrix(sparse=True, as_pixels=False).fetch('chr1') ``` it is crashing. The...

Hi, I am using Windows 10 and trying to install cooler package. When I try `pip install cooler` there seems a problem in installing 'pypairix' package and it is because...

**Hello, I am using "cootools cis_eigs" for a multi-weighted .mcool file,** "cis_eigs=cooltools.eigs_cis(clr,gc_cov,view_df=view_df,n_eigs=3) eigenvector_track=cis_eigs[1][['chrom','start','end','E1']]" **but I've received the following error:** "ValueError Traceback (most recent call last) ~/opt/miniconda3/lib/python3.7/site-packages/cooltools/api/eigdecomp.py in eigs_cis(clr, phasing_track, view_df,...

I get the following warning from making .mcool files - ``` WARNING:py.warnings:/mmfs1/home/asur/.virtual/python-3/lib/python3.8/site-packages/cooler/util.py:733: FutureWarning: is_categorical is deprecated and will be removed in a future version. Use is_categorical_dtype instead is_cat = pd.api.types.is_categorical(bins["chrom"])...

Hello, after I use cooler dump to extract data, what exactly does count mean in the generated text file? like this:count chrom1 start1 end1 chrom2 start2 end2 count chr21 5030000...