Reece Hart

_Original comment on Bitbucket by_ **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: --- @PeteCauseyFreeman Consider watching this issue.

Hi @AleksandrSl- I'm sorry about this issue. It sounds like you worked around it already. That db release was updated by a colleague, so I'm a bit fuzzy on details....

See also https://github.com/biocommons/hgvs/issues/537

Here's a much older set of slides with some possibly useful ideas: https://docs.google.com/presentation/d/17jdhX2ZcesuiEu_ZNniLBWsb9wwsez4SLrUNavY4mCc/edit

Totally agree. Normalization should > adjust values but not types

Agreed. We use "[residue](https://vrs.ga4gh.org/en/stable/terms_and_model.html?highlight=residue#residue)" to refer to both AAs and NAs. It looks like two occurrences of "base" crept in. Thanks for the notice.

Invitae (where I used to work) uses tx_similarity views often. In uta_20190926, they materialized that view for performance before making the database dump used for docker installs. In a large...

Recommend where? Throughout VRS? Strictly speaking, disallowing ambiguity codes would mean not being able to use GRCh references (which use ambiguity codes), so a global recommendation against them would be...

I'm surprised by your finding. Based on the query below, this appears to be an historical artifact that affected a small number of transcripts loaded before Aug 2016. I have...

Definitely part of a new release and carried into future releases. Thank you for the offer. I will take you up on PRs and offers to help eventually.