Reece Hart
Reece Hart
How to apply a protein change to a given amino acid sequence to produce a mutant amino acid sequence
I'm reading this as: you'd like to create a p. expression for an arbitrary protein change. Right? As you pointed out in #640, and discussed in #333, there's poor congruence...
FWIW, failure to account for indels in coding regions is the # 1 reason that hgvs differs from other tools. Our 2018 update paper provides lots of examples for issues...
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- Added Maximilian's instructions in 6b9445ac6b5c. Keeping open until resolved.
*Original comment by* **Maximilian Haeussler (Bitbucket: [maximilianh](http://bitbucket.org/maximilianh), GitHub: [maximilianh](http://github.com/maximilianh))**: ---------------------------------------- I am on OSX/Homebrew: brew install postgresql
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- I agree. Which platform are you on and what did you need to do to install PostgreSQL? I'll put that...
*Original comment by* **Maximilian Haeussler (Bitbucket: [maximilianh](http://bitbucket.org/maximilianh), GitHub: [maximilianh](http://github.com/maximilianh))**: ---------------------------------------- For me at least, it would be good if you document the psql dependency. The dependency itself is not a...
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- Update: Requiring postgresql native libs for all clients/users is clearly non-ideal. On the other hand, a significant portion of the...
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- Issue #229 was marked as a duplicate of this issue.
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- Issue #211 was marked as a duplicate of this issue.
*Original comment by* **Reece Hart (Bitbucket: [reece](http://bitbucket.org/reece), GitHub: [reece](http://github.com/reece))**: ---------------------------------------- See http://pythonhosted.org/setuptools/setuptools.html#declaring-extras-optional-features-with-their-own-dependencies