mixcr

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PoslavskySV

dbolotin

Longitudinal analysis

1

Simultaneous analysis of several samples Align individual samples: ``` mixcr align sample1_R1.fastq.gz sample1_R2.fastq.gz alignments1.vdjca mixcr align sample2_R1.fastq.gz sample2_R2.fastq.gz alignments2.vdjca mixcr align sample3_R1.fastq.gz sample3_R2.fastq.gz alignments3.vdjca ``` Assemble clones from all samples...

dbolotin

Refactor SingleDAligner using new aligner abstraction (with chains filter)

1

PoslavskySV

Non-functionality flags for clones and alignments

5

dbolotin

dbolotin

Add an explicit flag specifying that a CDR3 region is canonical

1

Needed for coding CDR3s only. Basically we need to check the following two things: * First and last codons are the reference ones (i.e. CDR3 is not trimmed in any...

mikessh

dbolotin

dbolotin

Assembling by clonal sequences without CDR3

1

dbolotin