mixcr
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MiXCR is an ultimate software platform for analysis of Next-Generation Sequencing (NGS) data for immune profiling.
"if V gene single primer / multiplex is used at 5’-end and adapters-present, the option value for floatingLeftBound will be set to true for V gene aligner parameters; in other...
Hi, I have used Mixcr multiple times, but never met the problem before. Now, I am sticking to this. I am running it in a private HPC with 256G memory,...
```mixcr postanalysis individual \ --metadata metadata.tsv \ --default-downsampling count-reads-auto \ --drop-outliers \ --default-weight-function read \ --chains TRA,TRB \ --only-productive \ --tables postanalysis/pa.i.tsv \ --preproc-tables postanalysis/preproc.i.tsv \ results/*.clns \ postanalysis/individual.json.gz ```...
Add clonality metrics to postanalysis, like Pielou’s index и Gini coefficient (can be found here https://www.sciencedirect.com/science/article/pii/S0958166920301051)
A metric that represents the abundance by tags (reads/umi/cells) of a given number of top clonotypes. Ex. what percentage of total reads accounts for top 10 clones ...
## Checklist before submitting the issue: - [✓] The issue is strongly related to the MiXCR software - [✓] The issue can be reproduced with [the most recent version](https://github.com/milaboratory/mixcr/releases) of...
In case of UMI based analysis export by default should include borh reads count and umi count with both frequencies calculated accordingly
Different facets should have different axis min and max values:
Add over-seq Qc report with plots. Number of barcodes per read\clonotype.