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See #689.

feature/-request
Port to SeqAn3

I am trying to build an FM-Index over a 13GB fasta file. After one hour of processing with an average cpu-load of only 52% on one core the indexer used...

enhancement
feature/-request
Port to SeqAn3

I get a compilation warning in include/seqan/sequence/sequence_lexical.h : 295. https://github.com/seqan/seqan/blob/584ae4fbff8312cfe31b3e0aea651edfb1b580ef/include/seqan/sequence/sequence_lexical.h#L295 I fixed the warning with: left_length = static_cast(right_length); Would that be the correct way of handling it? Thank you

feedback-required

using different cases is often done to express masking, it would be nice to have.

feature/-request
Port to SeqAn3

From Trac, @weese is this still an issue? In the case of paired reads where one mate aligns and the other does not, the SAM output of the FragmentStore is...

bug
Port to SeqAn3

The FragmentStore does neither support soft nor hard clipping. For soft-clipping, the full sequence is in the SEQ field of SAM files and the anchor gaps data structure supports clipping...

bug
enhancement
Port to SeqAn3

The names of the functions hash2, hash2Next, hashUpper and hash2Upper are not clear enough to get the idea immediately. As far as I understand, the function hash2 forces the computation...

enhancement
Port to SeqAn3

We need some means to align sequences against profiles. Here is some code: ​https://github.com/holtgrewe/align_profile

enhancement
feature/-request
Port to SeqAn3

The following task would be a nice advanced tutorial: Input are two FASTQ files with reads that contain paired reads which length ~100bp, template size ~150-300bp. Many of the pairs...

dox
feature/-request
Port to SeqAn3

When changing the underlying score type of a MatrixScore from standard `int` to `int16_t`, the SimdScoreWrapper issues a compile time error. Here the expected code: ```cpp Score mat{-1, -30}; ExecutionPolicy...

bug
compiler-warning