pgaudet

EC cross references in definition, not in general cross references

3

- [x] GO:0103040 aldose sugar dehydrogenase activity EC:1.1.5.- >> replaced EC def xref by MetaCyc, add PMID for e. Eoli paper since the UniProt entry P75804 has no EC or...

Add check for database definition cross references to also be a general cross reference

2

(to address https://github.com/geneontology/go-ontology/issues/28146#issuecomment-2233348302 requested by @sjm41 ) There are many cases where the definition cross references and the general cross references don't match. Minimally for - RHEA - EC -...

Remove incorrect EC mappings

1

See https://github.com/geneontology/go-annotation/issues/2828 * GO:0008725 | DNA-3-methyladenine glycosylase activity | IEA with 3.2.2.21 * GO:0052822 | DNA-3-methylguanine glycosylase activity | IEA with 3.2.2.21 * GO:0052821 | DNA-7-methyladenine glycosylase activity | IEA...

Fix definitions containing '2-trans,6-trans-farnesyl diphosphate ' to align with RHEA term label

1

The following terms use '2-trans,6-trans-farnesyl diphosphate' in their definitions, while RHEA uses '(2E,6E)-farnesyl diphosphate' - [ ] GO:0047461 (+)-delta-cadinene synthase activity - [ ] GO:0102879 (+)-thujopsene synthase activity - [...

Obsoletion request: GO:0052739 phosphatidylserine 1-acylhydrolase activity

2

Hi @tberardini , GO:0052739 phosphatidylserine 1-acylhydrolase activity has a single annotation to A. thaliana PLIP1 (AT3G61680) Is this really different from GO:0008970 'phospholipase A1 activity'? (Note that I made EC:3..1.1.32...

Hello, There are new relations in RO to capture regulation of process in other organisms: - regulates in another organism (RO:0002010) - positively regulates in another organism (RO:0012013) - negatively...

Hello, Splitting up work in the large table in #28340 This spreadsheet within the large table, named `2024-06-27 keep- need higher level mapping`, has 339 terms that we probably want...

- [ ] GO:0035896 positive regulation of mast cell degranulation in another organism >> obsolete and replace by GO:0044480 envenomation resulting in positive regulation of mast cell degranulation in another...

GO:0019933 cAMP-mediated signaling

33

Hello, Following on the Signaling workshop of the Fall 2017 (see slides here: https://docs.google.com/presentation/d/1xR6EFbRyCSwruXVeMYZtJfwWEbIr6U8zei8IwGG3OrA/edit#slide=id.g26be66c50c_0_6) and on #20487 "GO:0007188 adenylate cyclase-modulating" G protein-coupled receptor signaling pathway and "GO:0019933 cAMP mediated signalling"...

Query UBERON_0006174 pronephric sinus

8

**Uberon term** UBERON_0006174 pronephric sinus **Bug description** UBERON_0006174 pronephric sinus is causing some reasoning problems in GO (https://github.com/geneontology/go-ontology/issues/16524; GO:0039012 pronephric sinus development ), since it is classified as a space;...