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MACS -- Model-based Analysis of ChIP-Seq

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I'm running bdgcallpeak on a bedGraph file optained from an input normalised bigwig file (operation used was subtraction). The minimum value in the file is approximately -5000, and the maximum...

Feature Request

Hi, I used the following command to generate FE ppois signal track: `macs2 bdgcmp -t E1-H3K27ac_treat_pileup.bdg -c E1-H3K27ac_control_lambda.bdg -m FE -o E1-H3K27ac_FE.bdg` `macs2 bdgcmp -t E1-H3K27ac_treat_pileup.bdg -c E1-H3K27ac_control_lambda.bdg -m ppois...

`macs3 hmmratac --cutoff-analysis-only` always exits with exitcode 1 This is because of line 244 in `Commands/hmmratac_cmd.py`, which says to `sys.exit(1)` if `--cutoff-analysis-only` is specified. This causes issues when trying to...

Bug Report

Hi Tao, I used INPUT as my ctrl and used default parameters to call narrow peaks. I encountered a warning: Since the d(171) calculated from paired-peaks are smaller than 2*tag...

when using macs2 to call peak, it importError: /home/a123456/miniconda3/lib/python3.9/site-packages/MACS2/IO/ScoreTrack.cpython-39-x86_64-linux-gnu.so: undefined symbol: __log_finite, Which library should I install to get this symbol?

General Question

Hi, Thank you so much for developing the MACS3 HMMRATAC program! My ATAC-Seq data is from mouse ES cells. After running the cutoff analysis, I'm trying to use the fold...

General Question

Hi, If I don't have any input sample and use the -B option (macs2 callpeak -t -f BAM -g hs --outdir peaks -q 0.05 -n filtered -B), there are two...

Dear MACS3 developers, I encountered an issue while using macs3 bdgpeakcall with the --cutoff-analysis option. Specifically, I noticed that the generated cutoff analysis report always has the score values capped...

General Question

**Describe the bug** A clear and concise description of what the bug is. I tried to install MACS3 by running: conda install -c bioconda macs3 . It did not work....

Bug Report

Thanks for the work on such a useful tool. The pileup feature is failing for me when I use -f FRAG. This works for -f BED. See below. This failed...

Bug Report