Benjamin Buchfink

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I'm not sure I fully understand, can you run diamond with the `--log` option and send me the resulting `diamond.log` file?

The memory needed depends on the options `-b` and `-c`, it is roughly 20*b/c. I would not recommend splitting into files this size since diamond is more efficient when running...

> Are there any rough formulas you use when estimating memory consumption based on the -b -c parameters below Yes, see above.

I'm afraid there's no good solution for this, it's a known issue. You can try `--freq-masking`, see here: https://github.com/bbuchfink/diamond/wiki/Advanced-options If you only need clustering I would recommend using the clustering...

Are you using a BLAST database? If so, you need run run `makeblastdb` with the `-parse_seqids` option.

That would certainly be a useful feature, I will consider implementing it.

This is probably caused by the ranking heuristic, you can try using `--no-ranking`.

Database size also affects the evalue, so try to fix the size using `--dbsize`.

I can't reproduce the problem. If you send me the query file in question I can look further.

> Hi, I am getting the same issue. I have tested several versions. Have you solved the problem? > > Thanks What is your operating system and how did you...