Lee Newberg

`histomcis_stream` currently asks the user to create a set of nested dictionaries to specify study-wide and slide-wide parameters, and then works from there. Is this issues asking that instead of...

> I forgot this is software guide repo. This needs to be done in main repo too. Submitted as [ITK Issue #3239](https://github.com/InsightSoftwareConsortium/ITK/issues/3239)

Perhaps we are already thinking along these lines, but just in case ... we may want to go all verbose and say that there are two distinct cases here, depending...

In calculus `(x, y, z)` is usually associated with unit vectors `(i, j, k)` respectively. If that's the convention to stick with then ITK is `[IJK]`.

If the number of components is known before the file is read and unchanging then it might be better to use `Vector[itk.F,2]`.

Maybe it's not quite close enough to be of direct use, but in the context of machine learning and for getting the pixel data into Tensorflow, we do something similar...

Implementation goals: 1. Is implemented as a distinct filter, `StructurePreservingColorSeparationFilter`. 2. Accepts a single input image, but no reference image. That is, no color normalization is performed; if that is...

https://github.com/InsightSoftwareConsortium/ITK/pull/3479 should fix this issue. However, I nonetheless recommend that we use `if (!success) { itkGenericExceptionMacro(message); }` to replace `itkAssertOrThrowMacro(success, message);` in ITKColorNormalization code.

@guillermojp Thank you for your comment. Yes, I think this would make a nice addition to the current functionality. Unfortunately, I don't have the resources to pursue this at this...

That test might be resurrected with a little work. More generally, we should add a test with 3D images. Also, some examples from DigitalSlideArchive would be useful.