George Pimm

Hi @aforestsomewhere , What is the source of the pod5 data? has it been copied around, and could have become corrupted? The error `Invalid signature in file` suggests the header...

Hello @Taylorain , Pod5 does not and has never supported the VBZ compression directly. It has always used a derived VBZ-like compression style, which is slightly evolved from the original...

Hi @Taylorain, How have the pod5 files been managed since writing, are you sure they have not become corrupted during copy between machines? The messages above indicate to me the...

Hi @Taylorain, MinKNOW and pod5 files do not currently have integrity checking built in. You would need to run some kind of checksum (eg. `md5sum` on your files at source...

Hi @hasindu2008 , It looks reasonable, do you know the number of megabytes per second of signal you receive from the loading? This is a more interesting performance metric as...

If your CPU is maxing out, its more likely you are bottlenecking on decompression of signal - which you could confirm using `perf` tools, but you're right, for a single...

Hi @lpryszcz, This isnt something we expect, what is the length of reads in the file? What platform is the code running on, and where is the data stored (local...

Thanks - are you able to provide me permission to download files?

Hi @lpryszcz , Running this script: ```python if __name__ == "__main__": for file in sys.argv[1:]: begin = time.time() print(f"Processing {file}...") reader = pod5.DatasetReader(file) read_count = 0 for ri, read in...

Hi @KristinaGagalova, What is the origin of these files? Is it possible they are corrupt (given the output of `find_fas5_issues`). If you open the file in a tool like hdfview...