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Proteomics search software with integrated calibration, PTM discovery, bottom-up, top-down and LFQ capabilities

Results 189 MetaMorpheus issues
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Separation type isn't populated for calibration, isn't present at all for GPTMD or Glyco

Discussion

[iBAQ protein quantification](https://www.nature.com/articles/nature10098) excludes missed cleavages and normalizes intensities by the number of theoretical peptides, which correlates with length. It looks like proteins with many quantified missed cleavages peptides and...

Output Enhancement

This is the clearest explanation of a newer version of xcorr that has been implemented in a few different search algorithms including crux-tide. it is described in this paper: https://www.ncbi.nlm.nih.gov/pubmed/24895379...

Performance

If a peptide corresponds to the same range of multiple protein entries, the range of start-to-end only includes the unique ranges. I think having the start to end for each...

Bug

I'm trying to run calibration on a published phospho-enriched TMT dataset, and all but two of the files fail to calibrate. Has anyone else tried to run calibration on such...

Crash

Add command to download the latest version of MetaMorpheus to the command-line version. This will let us test the autoupdate function via appveyor and other automatic scripting/tests

Long-Term Stability
CMD

Search tolerances used in the .toml should be written to the results file description of the output. Also change Gptmd to G-PTM-D

Bug
Output Enhancement

All files - psms, protein groups, peptides.

Discussion
User-Friendliness

It'd be nice to add information on the estimated time remaining for completing the search in the Tasks section. The estimate could be based on 1) files already completed, 2)...

New Feature
User-Friendliness