MetaMorpheus
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Proteomics search software with integrated calibration, PTM discovery, bottom-up, top-down and LFQ capabilities
Hello, When trying to run an analysis using MGF file it crushes with this next error: Run failed, Exception: Input string was not in a correct format. However, when using...
water and ammonia loss peaks are prevalent in tandem mass spectra. However, including them during the search phase with primary ions leads to a loss in sensitivity. But, once the...
Appveyor wasn't building, hoping re-opening the PR will help
DOTF is implemented as the default in classic search. Errors in unit tests produced from this change are noted with a potential source.
Added functionality to classic search to allow for the use of decoy on the fly (DOTF). This should be entirely conservative of previous functionality with the exception of a change...
**What would you like to see done in MetaMorpheus?** **Please describe any alternatives you've considered** **Additional context**
Hi all, I'm currently benchmarking a variety of different proteomics search engines (Comet, MSFragger, IdentiPy, etc) for both speed & # of PSM identifications. I am struggling a bit (without...
Adding a new option in the search task window to adjust the required isotope threshold in FlashLFQ. MzLib still needs to be updated to accommodate this parameter.
Processing data from three co-IP different sample types, using MetaMorpheus v0.0.320, and searched against the Mouse proteome database (Mouse_SP_Jan2022), we noticed that some of the identified proteins (in the proteinGroups...