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Causal Mixture Model for GWAS summary statistics
Hi, Can the p-values for the variant overlap region be obtained from the Venn diagram for two tested traits? I'm asking because I'm trying to determine the likelihood of the...
Hi, Is there a function in MiXeR that could output the list of SNPs that are unique to trait1, trait 2 and shared between two traits? Could you please provide...
Hi, Guys, I got a `killed` massage when I ran: `python3 /precimed/mixer.py fit1 \ --trait1-file SSGAC_EDU_2018_no23andMe_noMHC.csv.gz \ --out SSGAC_EDU_2018_no23andMe_noMHC.fit.rep${SLURM_ARRAY_TASK_ID} \ --extract LDSR/1000G_EUR_Phase3_plink/1000G.EUR.QC.prune_maf0p05_rand2M_r2p8.rep${SLURM_ARRAY_TASK_ID}.snps \ --bim-file LDSR/1000G_EUR_Phase3_plink/[email protected] \ --ld-file LDSR/1000G_EUR_Phase3_plink/[email protected] \ --lib...
Hi I used cmake .. -DBOOST_ROOT=mixer/boost_1_68_0 && make bgmg -j16, then occured many errors there, I don't know why ,I will appreciate if you give me a favor, thanks ![image](https://user-images.githubusercontent.com/84009084/236658002-5276e3dc-386e-4ff7-b008-b4762baeec26.png)
Dear Oleksandr, I am using mixer to investigate the polygenic overlap between three traits. (trait1 and trait2; trait1 and trait3). I ran the analysis successfully, but the results is a...
I get this error: INFO:root:log_message(*********************************************************************** * mixer.py: Univariate and Bivariate Causal Mixture for GWAS * Version 1.2.0 * (c) 2016-2020 Oleksandr Frei, Alexey A. Shadrin, Dominic Holland * Norwegian Centre...
Hello, I am using linux aarch64 architecture. I create a virtual environment using miniconda3 in the linux. When I use CDLL(lib_path), I got the following error: The script is ```...
I followed the tutorial from the README page and got the results with no error. However, the Venn plot showed that the standard error is larger than effective numbers. How...
Hello, **trying to run mixer; I get a nice message :-(** Call: ./mixer.py fit1 \ --out SSGAC_EDU_2018_no23andMe_noMHC.fit.rep1 \ --lib /home/GENOME/mixer/src/build/lib/libbgmg.so \ --bim-file /scratch/GENOME/containers/reference/ldsc/1000G_EUR_Phase3_plink/[email protected] \ --ld-file /scratch/GENOME/containers/reference/ldsc/1000G_EUR_Phase3_plink/[email protected] \ --trait1-file SSGAC_EDU_2018_no23andMe_noMHC.csv.gz \...
Hi,I was wondering if the gene file could be processed as a whole, instead of being divided into 22 chromosomes. Thanks for your help.