pgaudet

@ValWood Can you please open a ticket in the ChEBI tracker and ask them to change the relationships? acyl-CoA ([CHEBI:17984](https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A17984)) should not be is_a adenosine 3',5'-bisphosphate ([CHEBI:37240](https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A37240)) (but I am...

Hi @rozaru Can you please tell me how you'd like to use this? We have not typically put outputs for degradation processes or inputs for synthesis processes; it's easy enough...

The problem is that our guidelines are not exhaustive enough. For the logical definition of a term, we need only to include how it's different from the parent, so for...

We can do this for now, but I think a less ambiguous solution would be to use 'de novo' biosynthetic process (no term yet, as far as I can tell)...

> Though I thought that most metabolic 'biosynthetic processes' were implicitly 'de novo biosynthetic processes' anyway - it's just that the 'de novo' prefix is explicitly added to distinguish those...

I guess my point is that from the LD you propose: intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_input CHEBI:57527 ! GDP-alpha-D-mannose(2−) intersection_of: has_primary_output CHEBI:57273 ! GDP-beta-L-fucose(2−) I dont know how...

Also - processing should not be under 'catabolic process' It *should* mean biosynthetic process/maturation. But we need to check that the annotations are consistent with this. Thanks, Pascale

There already is a TC - did you forget to link the ticket when you did the work? Thanks, Pascale

Hello @sylvainpoux We have a child term '[cytotoxic T cell pyroptotic process](http://purl.obolibrary.org/obo/GO_1902483)'; should this be inflammatory response or death?