pgaudet

Regulation with no annotations (and children not annotated): - [ ] regulation of advanced glycation end-product receptor activity 1 NAS @RLovering - [x] regulation of apurinic/apyrimidinic endodeoxyribonuclease activity - [x]...

Hi @pfey03 These will also be obsoleted. 'activation of' should be moved to 'x regulator activity'. Unfortunately these need to be manually reannotated as we cannot safely move a BP...

These have no remaining annotations, see https://github.com/geneontology/go-annotation/issues/5450 - [x] GO:0031552 negative regulation of brain-derived neurotrophic factor-activated receptor activity - [x] GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity -...

Obsoleted terms with no annotations: GO:0032431 | activation of phospholipase A2 activity -- | -- GO:2000984 | negative regulation of ATP citrate synthase activity GO:1905919 | negative regulation of CoA-transferase...

We can create a reaction with O-succinyl-L-serine, corresponding to https://www.rhea-db.org/rhea/53816 Would that work?

Created new term [Term] id: GO:0141223 name: cysteine synthase activity, acting on O-succinyl-L-serine namespace: molecular_function def: "Catalysis of the reaction: hydrogen sulfide + O-succinyl-L-serine = L-cysteine + succinate." [RHEA:53816] synonym:...

Well, cysteine synthase activity, acting on O-succinyl-L-serine is not using the same substrate - it's not a type of 'cysteine synthase activity': Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide...

We can rename "cysteine synthase activity" to "cysteine synthase activity, acting on acetyl-L-serine' to be more explicit. The reason why I hadn't done that is that this is the 'normal'...

@rozaru Regarding mannosyl diphosphorylinositol ceramide metabolic process: https://www.uniprot.org/uniprotkb/P38954/entry states: > Catalyzes the addition of a phosphorylinositol group onto mannosyl phosphorylinositol ceramide (MIPC) to form mannosyl diphosphorylinositol ceramide (M(IP)2C), the major...

Sorry for the long delay in my reply - "V-type ATPase complex disassembly" looks ok to me, based on the abstract. We may be conflating MF and BP here. It...