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Viral genome alignment, mutation calling, clade assignment, quality checks and phylogenetic placement

Results 200 nextclade issues
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When I upload a partial genome, it is not evident in gene view that there are missing parts. It looks like the sequence is equal to reference in parts that...

t:talk
package: nextclade_web

It's very cool that one can use the filter to look for sequences which have a particular AA or nuc change, but it would also be cool to filter for...

t:feat
good first issue
help wanted

@emmahodcroft noticed earlier that the run button was quite far down when one added the example sequences - the run button moves as you add files. And I just noticed...

t:feat
help wanted

`--output-csv` seems to be producing `;`-sep not `,`-sep The `--output-tsv` is fine. ``` % cd dattaset-dir % nextclade run --input-fasta seqiences.fasta ---dataset-dir . --output-csv out.csv % head out.csv seqName;clade;Nextclade_pango;qc.overallScore;qc.overallStatus;totalSubstitutions;totalDeletions;totalInsertions;totalFrameShifts;totalAminoacidSubstitutions;totalAminoacidDeletions;totalAmi ```

t:talk
docs

I've received a request for Avian flu datasets e.g. H5, via Twitter DM. If you'd like this feature, feel free to leave a thumbs up here to signal support.

t:feat
help wanted
package: nextclade
nextclade_data

When a site is N, rather than showing it as N in auspice.json produced by Nextclade, we give it the base of the attachment point. This threw me off when...

t:feat
package: nextclade

The clade schematic needs updating, we're using a pre-BA.4/5 version. Here's the new one: https://github.com/nextstrain/ncov-clades-schema

t:bug
good first issue
needs triage

Maybe not surprsingly, using standalone zstd for decompression and piping into nextclade is quite a bit faster than using the packaged zstd. I guess we could add some notes somewhere...

t:talk
package: nextclade_cli
package: nextalign_cli
os: macOS

With Beta 7, using the built-in compression is _slow_ when compressing to `xz` (using the default compression level). I'm running this in the context of a Nextstrain ncov workflow, and...

t:feat
good first issue
help wanted

I read through the help for `--output-all` but I'm not quite sure it explains well what the argument is supposed to be. I _think_ it's the directory that we want...

t:feat
package: nextclade_cli
docs