Michael Schubert

> Regarding the default of 2 mc.cores, that's not an issue since `mclapply` automatically checks for this. If length(X) == 1, then mc.cores defaults to `lapply` instead. That's true for...

Looking at e.g. `Slurm_lapply`, it seems I was wrong and chunking is supported :+1: Please document!

Thank you very much for your quick answer! Your code example helps me to solve my immediate task. For myself (and probably others) it would be great if you could...

My apologies for the late reply: The issue seems to be with `fastq` records that contain `N`s themselves: ``` # my.fq.gz @M00872:1070:000000000-GLPWM:1:1101:15776:1330 1:Y:0:1 AAGANNATNGNNGNNANNNTNNNAACGTAGTGCGCCAGCCTATTTCAGTGCTCAATCTTGCAGAGAATACTCTTGAGAGCG + AA1A##>>#>##A##A###A###ABBFFFHGGHEGGGGGGHHFHHHHHHHHHGFHHHHHHHHHHHCGHHFHHHGHHHHHHE @M00872:1070:000000000-GLPWM:1:1101:15866:1331 1:Y:0:1 AAGANNATNGNNGNNANNNTNNNAACGTAGTGCGCATAAGCCGTTCAAGAGGAGCCATTGTGGGGAGGCCCTGGGGACTGG +...

Good point, and there is ongoing work to enable at least [experimental LLVM 16 support](https://github.com/numba/llvmlite/commit/65bcb0318b2ea316f4bb578becc877051f61a122) (git head, no release yet). I intended to follow up this PR with adding [scanpy](https://github.com/scverse/scanpy)...

Ok. > That depends on how experimental it is I think that's the version that goes into the conda-dev channel with passing CI, so should be good enough > and...

There is a `python3.12` + `llvm16` [build in upstream CI now](https://github.com/numba/llvmlite/blob/69b8c1b370185c96cdbbd9de2d30e54803c30d43/azure-pipelines.yml#L23-L26), so I'd think this is stable enough to avoid `llvm15`

I updated the PR for `llvmlite=0.44.0` and `numba=0.61.0` using the `llvm-r1` eclass for `llvm=16` without patching upstream. This works on my install, feedback welcome!

~~@uis246~~ @littlewu2508 is it working for you now? I did not include the previous hacks, but I think I fixed your previous `undefined symbol` error

This is still an unresolved issue for us, so I checked the twobit files for the release now. The problem with those is that they do not provide methods to...