Matthew Brush

Results 112 comments of Matthew Brush

Nice write-up from Amos about getting cellosaurus into Wikidata, including several modeling issues and use cases: https://docs.google.com/document/d/1kEySzc0-yDEdLNPKKeAU-Mcm-c-dMHS64Ra85AV1RvM/edit

Does '**modifier**' mean that it affects the severity/presentation of the condition, but does not directly cause it? If so, consider http://purl.obolibrary.org/obo/RO_0003305 (contributes to severity of condition) `Def = a relationship...

For susceptibility, I think http://purl.obolibrary.org/obo/RO_0003306 ("contributes to frequency of condition") is the closes existing relation. `Def = a relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental...

Hi all. Had a quick chat with Chris today and we'd like to find a block of 2-3 hours for interested parties to tackle various issues related to G2P/D modeling...

Sounds like a nice fix for now. Will check back once implemented.

Perhaps you are getting all symptoms/indications for which these patients were treated, not just indications specific for imatinib? It looks like all of the items on your list of "indications"...

Hi Greg. Was the advice the AEOLUS folks provided w.r.t. how to filter indications from the outcomes results helpful? Are there other barriers to updating the mydrug data to filter...

Hi @stuppie. I think for Biothings your suggestion is best: > a given drug's doc should just have all outcomes and all indications as separate fields and the user of...

Good point @mellybelly - this data set would have much more predictive and analytical value if it we could stratify drug-outcome associations according to the indication for which the drug...

Thanks for the update @stuppes, and getting the indications into mydrug (is it called mychem now?). And for the nice analysis of how we might proceed with the more complex...