Matthew Brush

On 3-21-17 call, we decided that ClinGen would not assert a direction for evidence in its v1 model. ClinGen will just use the more generic has_evidence relation. The directionality can...

**Some additional notes from 4-3-17:** In the ACMG/ClinGen framework, the **direction** and **strength** of evidence is quite nuanced - dependent on the specific criteria used, the outcome determined, and the...

On 3-21-17 call, we decided that ClinGen would not assert a direction for evidence in its v1 model. ClinGen will just use the more generic has_evidence relation. The directionality can...

If alternate patterns for describing the same basic content are defined by SEPIO and allowed in practice, we will have to provide some means for post-hoc harmonization (e.g. defining property...

On 3-21-17 call, we decided that the v1 ClinGen model would implement the reified Contribution based approach.

Longer term we can explore refactoring of the structure of Assertions to make them more consistent and aligned with semi-formalized approaches to capturing assertion semantics, such as OBAN and SEPIO....

@larrybabb - mappings for all attributes are specified in the mapping spreadsheet. However, role, activity,and publication attributes are not included there. If you intend to include these as attributes of...

# `Proposition` - **Definition:** `Proposition` is an abstract entity representing the sharable meaning expressed in a particular assertion. **Examples:** **Description**: Propositions are sharable statements of purported truth. They represent the...

Thanks Larry. I think I got them all! On Thu, Aug 16, 2018 at 10:17 AM, Larry Babb wrote: > @mbrush FYI - the links you are using in the...

Noting that the phenotype-figure link is in the phenoGeneCleanData download [here](https://zfin.org/downloads/phenoGeneCleanData_fish.txt) - so for FISH with simple genotypes affecting only one native gene/locus, we can get this data here.