Matthew Brush

Results 112 comments of Matthew Brush

Ok. Thanks for the explanation @sebotic. I am starting to draft definitions for these relations and fit them into the RO hierarchy. One important distinction to make for a few...

Made some initial label and definition proposals in gdoc [here] (https://docs.google.com/document/d/1b_nrq97WWLlHCXzaAkCPyr6NAHJUz2KycKTdPVJE-OQ/edit#). Open for comment and discussion.

Making a formal proposal here for these ten drug-target interaction relations - including labels, definitions, and hierarchical classification. These relations will live under RO:0002448 ('molecularly controls'), and the textual definitions...

Just a note that we should we aware of additional drug-target interaction types as enumerated by other resources. DGIdb enumerates 33 ([link](http://dgidb.genome.wustl.edu/api/v1/interaction_types.json)) and Drugbank also has an enumerated type system...

@sebotic, others. Hoping someone can review the proposal [above](https://github.com/oborel/obo-relations/issues/144#issuecomment-280802009) . . . ideally someone with some domain knowledge in pharmaco-biology, but any second pair of eyes will do. Would like...

Found definitions for interaction types used at the DGIdb here: http://dgidb.genome.wustl.edu/getting_started (scroll down a bit for the definitions). Use these to vet the definitions proposed above.

My notes/conclusions from the 5-16 helpdesk call (@vdancik please correct any incorrect assumptions or conclusions): **Chembl** provides data about Assays that were performed to interrogate the affect a chemical perturbation...

@vdancik @sierra-moxon - This change to the name of this predicate slipped by me. I actually don’t think the label 'assesses' matches the predicate definition, nor does it accurately reflect...

Hi all. The original intent of the infores and retrieval provenance specifications was that *infores identifiers would be created for supporting data sources*, such as those mentioned above. The RetrievalSource-based...

@karafecho - can you clarify what you meant by: > COHD and ICEES KG are currently using the "supporting data source" slot to point to the corresponding wiki pages. Are...