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DeTiN is designed to measure tumor-in-normal contamination and improve somatic variant detection sensitivity when using a contaminated matched control.

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Hi, We use Canvas in our somatic CNA calling workflow. Is it possible to use the output of Canvas to create the aSCNA segmentation file required for detin? In particular,...

Hi I got this error message when running deTiN on my own data. I have tried it with the example_data and it runs fine and produces output. I think this...

hi, we just installed deTin recently. Python3.7 was required. We also installed all packages. When we tried to run the example data with the command recommended: python3.7 deTiN/deTiN.py --mutation_data_path example_data/HCC_10_90.call_stats.pon_removed.txt...

Hi, i have adjacent normal sample, so i want to check there is tumor in sample. so i try using deTiN, but gatk does not support AllelicCNV. and i try...

The VCF spec demands that the samples' column names match entries in the header (e.g. if `##normal_sample=MY_NORMAL` is present in the header, then the column for the normal should be...

I was wondering if and how it's possible to run deTiN using only SSNV data. Running deTiN without any input produces the error message "One of CN data or SSNV...