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Hello ESM team, Thank you for releasing the ESM3 code! I have a question regarding the training protocol you have described for the VQ-VAE model. In the paper, you describe...
Hi Team, Thank you for the excellent work on ESM3. I am currently comparing the performance of ESM3 on the CAMEO and CASP14 datasets with ESMFold and AlphaFold2. The CAMEO...
This PR enables ESM to run on Mac Silicon (M1, M2, M3) using the Metal Performance Shaders (MPS) backend for GPU training acceleration on Mac Silicon. PyTorch already supports Mac...
Hi, Is it possible to fine-tune or re-train the ESM-3 model with the protein sequence and structure or pdb file, and then apply the fine-tuned model to generate sequence or...
is there some global flag to make everything bfloat16. I recently had to go through the code an hardcode bfloat16... which seems kind of silly: Otherwise, I was getting bfloat16...
Fetching PDB files using ProteinChain.from_rcsb is a very convenient feature. However, many PDB files, especially those with complex and large structures, contain missing residues. For instance, I fetched one of...
specfic -> specific
There is currently no support for Apple Silicon Devices. If the team could add a check for mps devices, that would be great for Apple users
Hi, I was checking ESM-3 structure embedding, and ESM-3 sequence embedding, and found that the distance between embeddings is very less ( 0.0001) . I am curious how ESM-3 model...
For benchmarking purposes I would like to import both ESM2 and ESM3 but the problem is both have the same import name "esm" so I am unable to import ESM2....