C. Titus Brown

my understanding is that this basically requires docker. I'd be interested in a JupyterHub distribution that was docker based and could run on Jetstream, for this and other reasons. We...

> A quick thought here - if RStudio is officially _not_ supported by TLJH, I think we should have a note in the documentation somewhere saying this. A lot of...

hi @Amanda-Biocortex, yes, sourmash will not be able to distinguish two genomes that are nearly identical and have different names. However, since nearly identical genomes will have nearly identical taxonomic...

great! I'm going to leave this open for a bit, if you don't mind, so I'm reminded to update our internal docs with some of these opinions :)

related note in response to a private inquiry: `sourmash gather` followed by `sourmash tax metagenome` handles this quite well for taxonomic classification. This is (I can say with confidence) one...

I think this is a neat idea, and fits in with some other ideas we've had quite well. Just to start the discussion -- sourmash internals can totally support this!...

ref https://github.com/sourmash-bio/sourmash_plugin_branchwater/issues/637 and https://github.com/sourmash-bio/sourmash_plugin_branchwater/pull/458

Possible, but not proximal? :( You could split this into two distinct phases - 1. generating the sketches. This is in some sense easy, since you can easily write your...

hey @olgabot since you created this issue, we've improved the situation a fair bit by adding skip-mers to sourmash! It's still not _easy_, but it's not the impossible ill-defined situation...

had to re-enable the zenodo integration after I noticed that v4.8.6 didn't update. not sure I should bother uploading v4.8.6 to zenodo since last version is on there and presumably...