Lukas Heumos comments

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                                            Lukas Heumos

The one missing data issue to rule them all

@WeilerP no absolutely not and I accidentally didn't scroll far enough. Sorry and thanks! it's all good.

Intergrating strategy between AIR and transcriptomics

We'll look into this

Question about observed value and true expression value

Dear @caodudu, welcome to our field :) As you've outlined yourself, the actual distribution is unknown. Whether it's ZINB/Poisson or something else - who knows. They're all approximations of the...

Changed regex for calculation of percent hemoglobin genes

Dear @KriBaLin , thank you! `^HB(?!EGF|S1L|P1).+` seems a bit specific and I'm worried that there might be other genes that we're not excluding as False Positives here. Is this an...

Changed regex for calculation of percent hemoglobin genes

Guess one could look at Ensemble gene symbols to see how this regex would affect it. A list of genes is also possible but then we'd need the list ^_^

Changed regex for calculation of percent hemoglobin genes

Thank you very much @grst for the link! We'll make the changes accordingly using the list.

TCR/BCR enhancements

@zhouzhendiao the corresponding section in the not yet published manuscript: > AIRR sequences can be deciphered with V(D)J-sequencing followed by alignments and chain pairing. Although no benchmarks exist for TCR...

TCR/BCR enhancements

Thanks @zktuong - would you be interested in amending the content to ensure that it's factually correct?

Scaling TCR Dist

Dear @MiThoSan thank you very much for the positive feedback! This project is by more than just Theislab even though it's hosted in our Github organization. What have you tried...

Scaling TCR Dist

We can't do anything about this when their return is inconsistent. I am afraid that you'll have to open an issue over there and ask for guidance.