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Inference of ploidy and heterozygosity structure using whole genome sequencing data

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hi, everyone i running smudgeplot for my data, get strange smudgeplot. look the below ![1](https://user-images.githubusercontent.com/48479509/178419022-b7232879-f38d-4543-aee9-19a8fe37cfe0.png) i read the smudgeplot_warnings.txt, get information about provide the information for imporve the software. so...

Bumps [numpy](https://github.com/numpy/numpy) from 1.16.2 to 1.22.0. Release notes Sourced from numpy's releases. v1.22.0 NumPy 1.22.0 Release Notes NumPy 1.22.0 is a big release featuring the work of 153 contributors spread...

dependencies

Hi, my `smudgeplot.py hetkmers` job crashed multiple times because I ran out of memory. I manged to finally get it running by exclusively reserving an entire high memory node on...

![WhatsApp Image 2020-12-18 at 1 24 04 PM](https://user-images.githubusercontent.com/8181573/102619733-d0ac7500-4134-11eb-9d6c-92542624f8c0.jpeg)

wontfix

This seems a silly question, but I really confused with why I get a half estimated compared to the tutorial with the same commands. So I have followed https://github.com/KamilSJaron/smudgeplot/wiki/tutorial-strawberry to...

potential problems
smudgeplot included
genomescope included

I have had some troubles understanding my smudgeplot of a highly repetitive genome that has undergone LTR expansion recently. I counted 21-mers from 10x linked reads with the barcode information...

smudgeplot_included
genomescope_included

Some people run into troubles (#55) for picking L and U too close to each other and then non-having any kmers with low minor allele coverage ratio. I don't necessarily...

enhancement

We need some pilot examples that will go from raw reads to smudgeplot. We should do both those that are big and complicated as well as those that are small...

enhancement

As discussed in #65 I generalized the `middle_one_away` function to make parallelization possible. It is rebuilt as `get_pairs_at_pos` function and is now deterministic. Thus it contains a fix for #70...

The smudgeplot is now limited for heterozygosity only to certain extend (we extract kemrs that are 1SNP from each other). If the divergence of haplotypes is too great, we are...

enhancement
performance