C. Titus Brown

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* on farm head node, not on my laptop * easy to replicate - just follow release procedure install 😆 * no CPU usage, just hangs happens just after this:...

these are the latest versions of pytest and pytest-xdist.

no longer happening & not reproducible. 🤷

ref https://github.com/sourmash-bio/sourmash/issues/348

adding the `upset` command via the betterplot plugin in https://github.com/sourmash-bio/sourmash_plugin_betterplot/pull/35 - it produces figures like this: ![10sketches upset](https://github.com/sourmash-bio/sourmash/assets/51016/afeb536b-08c2-47de-9172-3305875d5d3d)

is this the same or a related issue? https://github.com/sourmash-bio/sourmash/issues/3398

my intuition suggests that, as long as the hashes are entirely independent (i.e. come from non-overlapping k-mers), this should be very reliable. @dkoslicki, we'll pass you the long-read paper results...

I put together some notebooks on detection _sensitivity_ [for 100bp reads](https://github.com/ctb/2022-sourmash-sens-spec/blob/main/detection.ipynb) and [for 10kb reads](https://github.com/ctb/2022-sourmash-sens-spec/blob/main/detection-10kb-reads.ipynb). As expected, genomes can be detected very _sensitively_ at _very, very_ low coverage. I think...

long read paper: Evaluation of taxonomic classification and profiling methods for long-read shotgun metagenomic sequencing datasets: https://www.biorxiv.org/content/10.1101/2022.01.31.478527v2 Relevant Figure 4 showing that sourmash has weirdly good performance 😆 -