Leighton Pritchard

Use read mapper as alternative to `PrimerSearch`

8

It should be possible to speed up the *in silico* hybridisation step by using `bwa` or similar to map candidate primers. The output of this step could be made to...

Several people have been confused between the stable and development branches of `pdp`/`find_differential_primers` (#48 #49 #51), so the documentation (and maybe repo structure) requires clarification.

To aid in maintenance/extension, using `mypy` static type-checking would be helpful.

It would be useful for broad screens to exploit NCBI's compute capacity by sending jobs to Primer-BLAST.

This option should allow for combinations of classes to be simultaneously identified using multiplexed primers that differ by size. This might take the form of: ```bash pdp multiplex --size-diff ```...

Use better logging exception format, as in https://realpython.com/python-logging-source-code/

After, or at the same time as, #40 it would be useful to have a Flask front end for interaction with results.

It would be useful to keep outputs in a suitable database backend, rather than in hundreds of different files on the filesystem.