varfish-server

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chore(main): release 0.1.0

3

:robot: I have created a release *beep* *boop* --- ## 0.1.0 (2024-02-08) ### Features * adapt filter frontend to case detail variant annotations ([#1104](https://github.com/varfish-org/varfish-server/issues/1104)) ([#1122](https://github.com/varfish-org/varfish-server/issues/1122)) ([ed0652a](https://github.com/varfish-org/varfish-server/commit/ed0652a32840e050f121ecf46160efca7f796e60)) * add api endpoints...

github-actions[bot]

Add QC metric "novel variant calls" (not in gnomAD etc.)

1

**Is your feature request related to a problem? Please describe.** It would be helpful to see this statistic as a QC metric. **Describe the solution you'd like** - Report number...

holtgrewe

Implement better monitoring for celery and redis

1

**Is your feature request related to a problem? Please describe.** It is currently not possible to see how busy a VarFish server is. **Describe the solution you'd like** Implement global...

holtgrewe

Absence of Heterozygosity (AOH) Calculation

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It would be helpful to calculate genomic intervals and total genomic content of absence of heterozygosity (AOH)/ Runs of homozygosity (ROH) in consanguineous individuals from the ES-data. The Lubski Lab...

boschann

Design "case manifest" file format and import API

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**Is your feature request related to a problem? Please describe.** We can currently (only) provide a PED file for describing a case. It would be very helpful to augment this...

holtgrewe

Implement "runs of homozygosity" feature

1

**Is your feature request related to a problem? Please describe.** Displaying runs of homozygosity would be useful. **Describe the solution you'd like** Implement this. **Describe alternatives you've considered** N/A **Additional...

holtgrewe

Efficient graphical overview of variant scores

1

The number of bioinformatics scores for describing a variant can be very large. Gaining a quick overview of a larger number of scores can quickly become unwieldy, as adding additional...

xiamaz

Document SAML setup for login

3

**Is your feature request related to a problem? Please describe.** SAML is useful for authentication. VarFish *should* already have support for it as sodar-core does. We have not tested this...

holtgrewe

Find second hit functionality not implemented yet

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Currently multiple users have experienced the find second hit functionality to time out on any variant. Steps to reproduce: 1. Use case https://varfish.bihealth.org/variants/f2acceb7-067d-41a4-8e39-236c022678f1/case/filter/fc4ec7e9-5f7c-4370-8e0b-1a2a0c96c42b# 2. Use clinvar pathogenic 3. Find second...

xiamaz

**Is your feature request related to a problem? Please describe.** In some situations it is desirable to clear the whole analysis history/status for the current user. One example is in...

holtgrewe