varfish-server

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**Is your feature request related to a problem? Please describe.** In the case that the query fails in the Vue.js filtration (e.g., non-validating schema), no good feedback is provided to...

holtgrewe

**Is your feature request related to a problem? Please describe.** The Vue.js variant filtration UI does not provide the features to download as file or export to MutationDistiller/CADD web server...

holtgrewe

**Is your feature request related to a problem? Please describe.** The Case Overview tab shows many relevant information regarding case details, pedigree, variant DB, SV release info, phenotype, comments, flags,...

your-highness

**Is your feature request related to a problem? Please describe.** The usage of DGV for excluding cases is problematic, e.g., in the context of microdeletion syndromes. Furthermore, the in-house filter...

holtgrewe

**Is your feature request related to a problem? Please describe.** It is relatively straightforward to create clinvar submissions from annotated variants. However, it is not easy to see which cases/variants...

holtgrewe

**Is your feature request related to a problem? Please describe.** In the new vue.js small variant filtration the "other carriers" tab of the variant details modal still requires implementation. **Describe...

stolpeo

**Is your feature request related to a problem? Please describe.** In the new vue.js small variant filtration the "second hit" tab of the variant details modal still requires implementation. **Describe...

stolpeo

Add de novo settings in annotation of case with HPO terms

1

**Is your feature request related to a problem? Please describe.** We are missing the following terms: - X-linked dominant inheritance/X-linked recessive => go away - Add X-linked, X-linked de novo...

holtgrewe

**Is your feature request related to a problem? Please describe.** Recent versions of VarFish Annotator write out an `callers` array rather than a `caller` string column (cf. bihealth/varfish-annotator#81, bihealth/varfish-annotator#83). **Describe...

holtgrewe

**Is your feature request related to a problem? Please describe.** The exon number `n of m` is important information for intepreting variants. It is currently not displayed. **Describe the solution...

holtgrewe