core-package topic
BiocParallel
Bioconductor facilities for parallel evaluation
Biostrings
Efficient manipulation of biological strings
GenomicRanges
Representation and manipulation of genomic intervals
GenomeInfoDb
Utilities for manipulating chromosome names, including modifying them to follow a particular naming style
Rsamtools
Binary alignment (BAM), FASTA, variant call (BCF), and tabix file import
SummarizedExperiment
SummarizedExperiment container
GenomicFeatures
Conveniently import and query gene models
VariantAnnotation
Annotation of Genetic Variants
DelayedArray
A unified framework for working transparently with on-disk and in-memory array-like datasets
IRanges
Foundation of integer range manipulation in Bioconductor