Timo Sachsenberg
Timo Sachsenberg
fixed in pandoc... need update in action
also check if it makes sense to print key, value, description in ``` __repr__ or __str__ ``` e.g., users want to write print(myParam) ``` def __str__(self): return list(zip(p.keys(), p.values(), p.descriptions()))...
probably needs more thinking
Isobaric labeling The idea of isolaric labeling is to label the different samples with labels of the same mass. We design the label in a way that they fragment differently...
iTRAQ Isobaric tags for relative and absolute quantitation (iTRAQ) is a very commonly used isobaric labeling method in quantitative proteomics. It uses stable isotope labeled molecules that can be covalent...
Protein inference problem Peptide identification methods only match peptides to spectra and output a ranked list of PSMs with corresponding scores. Then false discovery rates can be computed and help...
Significance What is the meaning of a PSM for a protein identification? The FDR is calculated on the PSM level and 1% FDR means that one in 100 PSMs yields...
One hit wonders In many cases, proteins are identified through a single PSM: if a protein contains at least one identified PSM, it is accepted as an identification. These ‘single...
todo: check out  fix warnings and prevent building (exit code 1) if warnings are reintroduced