Omer Weissbrod

Results 19 comments of Omer Weissbrod

Hi @jerome-f, This sounds like a great idea. I never tried using the FINEMAP estimates with SuSiE, but I don't see a reason why it wouldn't work... But I guess...

Hi @gmgaous, I am not sure if this approach will work. As mentioned in private communication, thing paper might be helpful: [https://www.nature.com/articles/s41467-021-23134-8](https://www.nature.com/articles/s41467-021-23134-8)

Hi @dietina, I would need more information to help reproduce this... Can you run the example pipeline without an error? If yes, can you please prepare a short reproducible example...

@dietina, you can send example data to [email protected]. I suspect that this is somehow related to long-range LD regions: Both chromosomes 6 and 11 have such regions (as well as...

@liqingbioinfo please feel free to send me a reproducible example, and I'll try looking into it

Sorry, I can't do anything until I have a reproducible example in hand...

Hi Joni, I can add support for .bcor files but I need to think about what the interface should look like. Can you please explain how the data is arranged...

Hi, I added support for computing LD-scores from an arbitrary set of input .bcor files. Please see the end of the [updated wiki page](https://github.com/omerwe/polyfun/wiki/2.-Using-and-creating-functional-annotations) for details, and please let me...

Hi Joni, Not a problem, but I'm surprised that the loading of .bcor files is the memory bottleneck. .bcor files are packed pretty efficiently, I don't think they have any...

Hi Joni, Sorry for this. I didn't write the .bcor code (it was written by the author of LDstore), so I don't know it that well. However, looking at the...