Oliver Hofmann

Yay! Super excited for you, congrats!

Adding a +1 to this, see our discussion with the PCGR developer at https://github.com/sigven/pcgr/issues/12. vcfanno seems ideally suited to sidestep the issue of having to develop a custom framework to...

Any thoughts on this behaviour before we explore workarounds with the workflow engine?

Thank you for starting the discussion, @tskir - very much in support of this and would love to see this integrated with the refget services.

I tend to be more in favor of the first proposal - define the inputs / outputs now and make the adjustments instead of creating another model / framework to...

I can't believe I am arguing for this change but here we are. Of course, noodles is doing the right thing here and there is a strong case for having...

> @ohofmann out of curiosity, is your issue with the header the same as @sc13-bioinf‘s (the lowercase platform name)? Yes, weirdly enough the same issue - this is for a...

Nice writeup. I still value in ensemble calls for cases where you need an all purpose method and are not able to tweak parameter settings to your specific library prep...

We've been discussing the lack of support for VCF 4.4 in IGV (https://github.com/igvteam/igv/issues/1289) and started looking at the current htsjdk / VCF interaction. This PR looks like a major step...

@cmnbroad Thanks for the update! It does help, though we may have to consider postponing the VCF 4.4 announcement / PR drive. I wouldn't want the first experience of many...