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RO is an ontology of relations for use with biological ontologies

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``` tomc@cypher ~/junq $ cut -f3- -d' ' ro.nt | wc -l 5280 tomc@cypher ~/junq $ cut -f3- -d' ' ro.nt | grep "^

pipeline

Is RO intended to house ALL relations used in OBO ontologies? Different branches of RO have different levels of specificity, which may simply reflect demand. However, it seems that some...

discussion
website/documentation

See https://github.com/CommonCoreOntology/CommonCoreOntologies Note that they are using the 2005 set of relations with the old URIs https://github.com/CommonCoreOntology/CommonCoreOntologies/blob/master/BFO%20Version/ro.owl I will alert them these are no longer supported This has a lot...

environment
rule

first ideas: is agent of is patient of is principal participant of

discussion
GO

RO has many SWRL rules. These are only visible in Protege if you go to Views and select Rules: ![image](https://user-images.githubusercontent.com/50745/46100671-cc27ca80-c17e-11e8-9dec-0377938df449.png) Note most of the rules are annotated The rules don't...

enhancement
website/documentation
rule
pipeline

Currently RO has the term "contributes to condition" which is a parent of: - contributes to frequency of disease - contributes to severity of condition - ameliorates condition - exacerbates...

phenotype
change request

experiment: try defining participation relations in terms of roles. E.g. p has-output c p has_participant (c and has_role some r) This could be seen as pointless semantic shuffling, but there...

change request
stale

It would be useful to have a relationship to link an instance of a phenotype to the frequency seen in a cohort of patients diagnosed with a condition. This could...

new term request
phenotype
stale

The plant trait ontology people need to relate the expression of a trait to an environmental stimulus it is expressed in response to. see https://github.com/Planteome/plant-trait-ontology/blob/add-dp/patterns/response.yaml I don't believe we have...

phenotype
environment

Are there any guidelines for using parasite relations vs pathogen relations? Is pathogen_of restricted to single-celled organisms? Where do we want to draw the line? The example I'm thinking of...

question
environment