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Viral genome alignment, mutation calling, clade assignment, quality checks and phylogenetic placement

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We might want to give users a hint that Nextclade requires a lot of memory in case there are many sequences. We can simply take fasta files size and upon...

t:feat
good first issue
help wanted

Love the use of WASM for nextalign! I was wondering whether you had tried/considered turning exception handling off when compiling your code (`-s DISABLE_EXCEPTION_CATCHING=1 -fno-exceptions`)? Anecdotally, I've found this has...

t:feat
good first issue
help wanted

It may help bug fixing if we generate informative error logs that users can share by clicking a button. Users could optionally submit the sequences in question as well if...

We had issues with adblocker browser extensions and Brave browser breaking Nextclade. Privacy protection features don't treat Nextclade's client-side computation model well. Nextclade performs a lot of calculations in the...

t:feat
good first issue
help wanted
package: nextclade_web

Right now, it's not possible to open the tree view in a new tab without having to do the whole alignment again. Use case: I have two screens and would...

t:feat
good first issue
help wanted

Related: https://github.com/nextstrain/nextclade/issues/439 We might want to warn users when features required for Nextclade to function are unavailable in their browsers. Nextclade needs WebAssembly and WebWorkers, so these are the obvious...

t:feat
good first issue
help wanted

The tree page containing phylogenetic tree rendered by Auspice takes a couple of seconds to navigate to. In Nextstrain, it does not seem to be the case, even if a...

t:feat
good first issue
help wanted
package: nextclade_web

Despite Nextclade being a [single-file download](https://github.com/nextstrain/nextclade/releases), we might also consider packaging it for even simpler installation. The [data](https://github.com/nextstrain/nextclade/tree/master/data) downloads and updates might need to be handled there. We might package...

t:feat
good first issue
help wanted
package: nextclade_cli

Despite Nextalign being a [single-file download](https://github.com/nextstrain/nextclade/releases), we might also consider packaging it for even simpler installation. We might package for: - Conda - Homebrew - Various Linux distros with deb...

t:feat
good first issue
help wanted
package: nextalign
package: nextalign_cli