Ha X. Dang
Ha X. Dang
This is a known bug when only one sample is provided. I am working on a fix. In the meanwhile, you can try to add a fake sample identical to...
Hi @amanda-fitz, I am not sure if I understand your question completely, but: (1) clonevol doesn't perform clustering. It takes the clustering from pyclone and reconstruct the concensus clonal evolution...
1) ClonEvol doesn't reassign cluster IDs, so the IDs in all plots should match those from Pyclone. One thing I should note is that ClonEvol requires contiguous integer as cluster...
Thanks for reporting the issue. I will note this as a bug.
Could you send complete code and input file so I can reproduce the exact error?
I couldn't reproduce the exact error you reported, however, there were a few things missing in your code that produced a different error (see how sample.groups is passed). I consider...
Hi @DawnMKing , Thanks for reporting. I am aware of this issue and will fix it in the next major release.
Hi @logan-leak, This is a known issue with ClonEvol. At some point, the implementation of bootstrapping dropped support for single sample analysis. One trick to overcome this is to create...
If you want to analyze individual patients' clonal evolution/admixture using single sample, ClonEvol is still useful. Then you can compare the clonal evolution/admixture between pre- and post-treatment groups and see...
ClonEvol supports both mono- and poly-clonal model cancer initiation (parameter cancer.initiation.model='polyclonal' in infer.clonal.models). Is that what you meant?