Ivan Grishagin issues

Results 77 issues of


                                            Ivan Grishagin

Add DESI ingredients (curated) to stitcher

https://docs.google.com/spreadsheets/d/1muq9bPsbSG4tjA0ClLedux1nlMrdl5Q2hX9IYJr6jec/edit#gid=201043048This is an annotated list of drug ingredients for products considered through DESINoel

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Add Rancho Curated NDAs to Inixight

The product of Federal Register Scraping and manual curation ... these NDAs should be tracked in Inxight

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Add clinical trials

https://spotlite.nih.gov/ncats/inn-scraper/blob/master/fetchClinicalTrials.shThis provides an update to the UNII_CT_MAPPING.txt.zip file

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2019-10-04 Fix PROBLEMS with Descriptions, Targets

Rancho was assigned two tasks:[COMPLETE] Add missing Descriptions to substances with known approval status [IN PROGRESS] Add Targets (NCATS190415 list)Reports (including preliminary) are attached.Rancho found a handful of problematic entries,...

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Clean up target names

Many target names appear to free text ... can we normalize them?Search Primary Target...Glycine transporter 1Sodium- and chloride-dependent glycine transporter 1These are the same target, I think. Can we algorithmically...

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Tocopherol Acetate does not map to Tocopherol

So its not a big deal that this ester doesn't map to its free acid. We do a good job catching some of these esters -> parent free acids by...

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CFR list of withdrawn for safety or efficacy

https://www.govinfo.gov/content/pkg/CFR-2019-title21-vol4/xml/CFR-2019-title21-vol4-sec216-24.xmlIs this list currently included into the application?For background on process ... see:https://www.google.com/search?rlz=1C1GCEU_enUS851US851&ei=vY65XfOjM4fl5gLY4qDwDw&q=site%3Afederalregister.gov+%22FDA+will+not+accept+or+approve+abbreviated+new+drug+applications+%28ANDAs%29%22&oq=site%3Afederalregister.gov+%22FDA+will+not+accept+or+approve+abbreviated+new+drug+applications+%28ANDAs%29%22&gs_l=psy-ab.3...3611.4057..4586...0.0..0.44.163.4......0....1..gws-wiz.52kH9jLwsXA&ved=0ahUKEwiz9sCSisTlAhWHslkKHVgxCP4Q4dUDCAs&uact=5https://www.federalregister.gov/documents/2018/10/29/2018-23528/endo-pharmaceuticals-inc-et-al-withdrawal-of-approval-of-10-new-drug-applicationshttps://www.federalregister.gov/documents/2014/07/02/2014-15371/additions-and-modifications-to-the-list-of-drug-products-that-have-been-withdrawn-or-removed-fromhttps://www.federalregister.gov/documents/2018/12/11/2018-26712/list-of-drug-products-that-have-been-withdrawn-or-removed-from-the-market-for-reasons-of-safety-or

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