erlun1

Error in plotEnrichHeatmap:

1

Problem: After running the code: enrichMotifs

ConstructNetwork() and ModuleEigengenes() functions use different methods to calculate the ME (module eigengene), leading to the discrepancy in the kME result

3

Thank you very much for developing the hdWGCNA package. However, I have encountered an issue with the conflicting ME (module eigengene) and kME (module membership) values during the module identification...

How to Add sequence_id Information to mudata['airr'].obsm['airr'] When Reading 10X VDJ Results

1

Thank you for providing such an excellent module as scirpy. I recently upgraded from version 0.11.2 to 0.20.0 and noticed that scirpy now uses an awkward array to store IR...

Severe Performance Issues in IntegrateLayers and Sketch with Large-scale Data (2.2M Cells, 281 Samples)

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Description:​​ We are experiencing critical performance bottlenecks when using IntegrateLayers with SketchData for Harmony integration on a large single-cell dataset (2.2 million cells across 281 samples). Key observations: ​Excessive Runtime...