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add other summary cohorts

Open brentp opened this issue 9 years ago • 3 comments

e.g. UK10K: ftp://ngs.sanger.ac.uk/production/uk10k/UK10K_COHORT/REL-2012-06-02/ this will make max_aaf_all more powerful for whole-genome studies.

brentp avatar Feb 08 '16 16:02 brentp

Is it a VCF with frequencies? I can't open the link

arq5x avatar Feb 09 '16 03:02 arq5x

It is. VT decompose then we do something like

gemini annotate -f UK10K_COHORT.20140722.sites.VT.confint.vcf.gz -o min,min,min -t float,float,float -e AF,AF_lowCI,AF_upCI -c UK10K_AF,UK10K_AF_lowCI,UK10K_AF_upCI $INPUTPROJECT.VT.VEP.db

jxchong avatar Apr 15 '16 22:04 jxchong

I hear two WGS databases of ~20k samples each are coming out soonish.

jxchong avatar Apr 15 '16 22:04 jxchong