Isaac

oh, I see the similar question have been discussed before, but I have some extra questions I want to confirm: 1.As mentioned earlier, phenotypes that are all zeros will be...

> 1. It looks like `Trait1` does not have any significant cells. Can you clarify what you mean that "they are significant on certain cell groups"? > 2. The power...

> Thanks for the clarification. > > > 1.Yes, trait 1 does not exhibit significant cells across all cell types. However, at the same time, it is significant in some...

> `assoc_mcp` and `assoc_mcz` in the produced dataframe are at the nominal level (so you need to convert them to FDR by yourself). > > But the plotting function would...

I also want to consult how to understand sigma matrices? In my idea, the omega matrix represents the degree of correlation between phenotypes, with a larger absolute value indicating a...

I have encountered a situation similar to #124 , where the max FDR for a single trait has exceeded 0.05. May I inquire whether I can use the max FDR...

Adding a supplement to this issue: the univariate max FDR for trait1 and trait2 is 0.2751 and 0.4192, respectively. However, after MTAG, they become 0.0239 and 0.0413, as mentioned in...

> I think that the likely issue here is that both of your phenotypes are quite low powered, so the estimates of Omega and Sigma are noisy. Omega may be...

> I am also confused. What's the SE on the LDSC estimate? Can you post the complete MTAG log? Hah, I'm so sorry for causing confusion for you. According to...

> I am also confused. What's the SE on the LDSC estimate? Can you post the complete MTAG log? This is the log file for calculation of rg between trait1...