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                                            Manoswini-02

HG38 to CHM13v2 VCF liftover using chain

@jamesdalg have you checked the chromosome notation of all the given files? They have to be same for proper mapping. It looks like one of your input files might have...

Much lower pass rate of 5hmC calls than 5mC calls

Hi @hassebossenbroek > On average, 82% of 5mC calls pass, whereas only 36% of 5hmC calls pass. Is this data from all samples? The statistics provided for a representative sample...

Clarifications on DMR Analysis

@ArtRand , @PRIYANKA-22091995 I'm also looking for 5hmC-associated-DMRs. In this regard, the modbam2bed tool offers an option (-m) to target specific modified base types. For eg, if my focus is...