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Communitiy-based Cell Line Ontology

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modified HeLa cells needs update to the HeLa cell, the genetic transformation, citation. Cell label Cell CLO ID Parent cell label Parent cell CLO ID Transformation Genetic Modification(s) Reference In...

Different naming style HME1; hTERT-HME1 Same catalog: ATCC CRL-4010 http://www.ontobee.org/ontology/CLO?iri=http://purl.obolibrary.org/obo/CLO_0004291 http://www.ontobee.org/ontology/LINCS-CLOview?iri=http://purl.obolibrary.org/obo/CLO_0037172 "comment: disease: TERT immortalized" This is not a diseased cell line, but normal breast cell line immortalized with hTERT

Both are from a 53 year old male with adenocarcinoma http://www.ontobee.org/ontology/LINCS-CLOview?iri=http://purl.obolibrary.org/obo/CLO_0009964 http://www.ontobee.org/ontology/CLO?iri=http://purl.obolibrary.org/obo/CLO_0004305 http://www.atcc.org/Products/All/HTB-40 http://cancer.sanger.ac.uk/cell_lines/sample/overview?id=907073

need to define it as an in vitro cell, definition can consider EFO: induced pluripotent stem cell: http://www.ebi.ac.uk/efo/EFO_0004905

enhancement

We should put the merged file into release folder, and other files into dev folder, otherwise, people will continuously asking the import files questions.

Many cell line cell entries are missing neccessary annotations (organism, cell type, disease, etc). They only contains ATCC xRef via seeAlso property. This is a major fault.

bug

The cultured cell in CLO is under two terms: http://www.ontobee.org/browser/rdf.php?o=CLO&iri=http://purl.obolibrary.org/obo/CL_0000010 This term is from CL, but in CL it has only one mother term: experimentally modified cell in vitro. Please...

bug

The OBI term http://purl.obolibrary.org/obo/OBI_0001869 should be deleted from CLO.

bug

A9 cell: ``` http://purl.obolibrary.org/obo/CLO_0001618(CLO) http://purl.obolibrary.org/obo/CLO_0001619(CLO) ``` A6 cell: ``` http://purl.obolibrary.org/obo/CLO_0001602(CLO) http://purl.obolibrary.org/obo/CLO_0001603(CLO) ``` 15C6 cell: ``` http://purl.obolibrary.org/obo/CLO_0001108(CLO) http://purl.obolibrary.org/obo/CLO_0001109(CLO) ``` DS-1 cell: ``` http://purl.obolibrary.org/obo/CLO_0002821(CLO) http://purl.obolibrary.org/obo/CLO_0002822(CLO) ``` GM00425 cell: ``` http://purl.obolibrary.org/obo/CLO_0003510(CLO) http://purl.obolibrary.org/obo/CLO_0026109(CLO) ```...

duplicate

This definition needs to be distinct with the definition of cell line. --- generated at CLO refactory call on 5/26/2015

enhancement