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Ten Quick Tips for Deep Learning in Biology

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**Have you checked the [list of proposed rules](https://github.com/Benjamin-Lee/deep-rules/issues?q=is%3Aissue+is%3Aopen+label%3Arule) to see if the rule has already been proposed?** - [X] Yes **Did you add yourself as a [contributor](https://github.com/Benjamin-Lee/deep-rules/blob/master/contributors.md) by making a...

Tip

**Have you checked the [list of proposed rules](https://github.com/Benjamin-Lee/deep-rules/issues?q=is%3Aissue+is%3Aopen+label%3Arule) to see if the rule has already been proposed?** - [x] Yes Use a simple, linear model, e.g., (multinomial) logistic regression or...

Tip

**Have you checked the [list of proposed tips](https://github.com/Benjamin-Lee/deep-rules/issues?q=is%3Aissue+is%3Aopen+label%3Atip) to see if the tip has already been proposed?** - [x] Yes **Did you add yourself as a [contributor](https://github.com/Benjamin-Lee/deep-rules/blob/master/contributors.md) by making a...

Fun example that highlights over fitting (not DL specific) https://twitter.com/harmonslide/status/1092178779382972417?s=19

Not all problems are equally amenable to deep learning. Make sure that there is a high prior probability that your problem will benefit from deep learning. Some useful rules of...

Tip

From November 2018: https://journals.plos.org/plosmedicine/issue?id=10.1371/issue.pmed.v15.i11 More focused on medicine than biology, but has some interesting points. I read the editorial https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002721, which references some of the papers in the issue, including...

paper

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2718342 (very short) We're focusing in biology, not medicine, but some of this is relevant: Data quantity: > Applying deep learning techniques to more complex and heterogenous disease states, such...

**Have you checked the [list of proposed rules](https://github.com/Benjamin-Lee/deep-rules/issues?q=is%3Aissue+is%3Aopen+label%3Arule) to see if the rule has already been proposed?** - [X] Yes **Feel free to elaborate, rant, and/or ramble.** **Any citations for...

Tip

Deep learning methods are notably difficult to interpret. If data is provided without explicitly engineered features, how are you going to address finding any biases in predictions? What sort of...

Tip

https://doi.org/10.1038/s41588-018-0295-5 > Deep learning methods are a class of machine learning techniques capable of identifying highly complex patterns in large datasets. Here, we provide a perspective and primer on deep...

paper